Glycosyl compounds
Medchemexpress LLC 8-Azaadenosine 10Mm In 1Ml Dms | HY-115686-10MM/1ML
8-Azaadenosine 10Mm In 1Ml Dms
Apexbio Technology LLC 5-Azacytidine 320-67-2 10mM (in 1mL DMSO)
5-Azacytidine is a cytidine analog compound that functions as an inhibitor of DNA methyltransferase (DNMT) Its mechanism involves incorporation into cellular DNA/RNA followed by covalent binding to DNMT through the formation of a bond between the C6 position of 5-Azacytidine and the thiol group of cysteine residues in DNMT enzymes leading to reduced DNMT activity and subsequent DNA demethylation In cellular studies involving multiple myeloma (MM) 5-Azacytidine exhibits cytotoxicity against MM-derived cell lines (MM 1S MM 1R RPMI-8266 RPMI-LR5 RPMI-Dox40) with reported IC50 values of approximately 1 5 mol/L 0 7 mol/L 1 1 mol/L 2 5 mol/L and 3 2 mol/L respectively as well as patient-derived MM cells (IC50 1 5 mol/L) This compound is widely used in cancer research to investigate epigenetic regulation mechanisms and DNA methylation pathways
Cayman Chemical 7-keto Cholesterol 5mg
A bioactive oxysterol; a major oxysterol component of oxidized LDL; produced by oxidation of cholesterol via ethanol-mediated lipid peroxidation or photodamage as well as oxidation of 7-dehydro cholesterol by CYP7A1; inhibits CYP7A1 (IC50 = ~1 μM); induces activation and chemotaxis of retinal microglia as well as polarization to a pro-inflammatory state; increases ocular levels of VEGF, IL-1β, and GRO/KC, macrophage infiltration, and neovascularization in rat eye; levels are increased in lipid deposits in a variety of chronic diseases
Medchemexpress LLC Α-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl 4-chloro-4-deoxy- | 56038-13-2 | 397.63 | 5 G
Sucralose is a non-nutritive artificial sweetener and sugar substitute. It can activate a conserved neural fasting response, leading to an appetite-stimulating effect in rodents. It is for research use only.
- Non-nutritive artificial sweetener
- Sugar substitute
- Activates conserved neural fasting response
- Purity: 98.0%
- Appearance: White to off-white solid
Sigma Aldrich Fine Chemicals Biosciences IPTG | 367-93-1 | MFCD00063273 | 10g
IPTG | Purity: 99% | Mol Wt: 238.3 | 367-93-1 | MFCD00063273 | 10g
![Alkali Scientific IPTG [Isopropyl β D thiogalactopyranoside], Dioxane Free, 500 Milligrams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659969.jpg-250.jpg)
Alkali Scientific IPTG [Isopropyl β D thiogalactopyranoside], Dioxane Free, 500 Milligrams
IPTG (Isopropyl β-D-thiogalactopyranoside) is a gene expression inducer commonly used in molecular biology to activate lac operon-based gene systems in bacteria. IPTG binds to the lac repressor protein, causing the repressor to release from the lac operator, enabling gene transcription. The dioxane-free formulation ensures that the reagent is free from harmful contaminants, making it safer for laboratory use. The 500mg quantity is ideal for preparing multiple solutions for high-throughput experiments or bacterial cultures. IPTG is essential in protein expression studies, particularly in systems using E. coli for recombinant protein production, offering a reliable and efficient inducer for gene activation.
Alkali Scientific IPTG (Isopropyl β D thiogalactopyranoside), Dioxane Free, 1 G
IPTG (Isopropyl β-D-Thiogalactoside) is a molecular biology reagent used as an inducer of gene expression in systems utilizing the lac operon. IPTG is not metabolized by bacterial cells, which makes it a potent inducer of gene expression without being consumed in the process. This 1g bottle is ideal for laboratory experiments involving the expression of recombinant proteins or enzymes in bacteria or other systems. By adding IPTG to culture media, researchers can activate the expression of genes under the control of the lac promoter, facilitating the study of protein function, enzyme activity, or gene regulation. IPTG is a standard reagent used in cloning, protein purification, and gene expression research.
Alkali Scientific IPTG (Isopropyl β D thiogalactopyranoside), Dioxane Free, 25 G
IPTG (Isopropyl β-D-thiogalactopyranoside), Dioxane Free, 25g, is a molecular biology reagent widely used to induce gene expression in bacterial systems. This dioxane-free formulation is especially beneficial for experiments where the presence of toxic solvents may interfere with the results. IPTG functions by binding to the lac repressor, triggering the expression of lac operon-controlled genes, a common technique in protein expression studies. The 25g packaging is ideal for smaller-scale research or laboratories with limited usage requirements. This compound is essential for recombinant protein production, gene expression analysis, and other molecular biological studies.